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DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA

The aim of this study was to obtain the sensitivity data of the native strains of R. microplus to ivermectin (IVM) in the province of Santa Fe-Argentina, in order to detect the emergence of resistant strains. Native (field isolation) and susceptible (reference) larvae of R. microplus were treated wi...

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Autor Principal: Torrents, J
Formato: Artículo revista
Publicado: Universidad Nacional del Litoral 2021
Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10944
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spelling oai:bibliotecavirtual.unl.edu.ar:article-109442021-12-06T19:18:04Z DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA DETERMINACIÓN DE LA CONCENTRACIÓN EFECTIVA 50, 90 Y 99 DE IVERMECTINA SOBRE UNA CEPA DE GARRAPATA COMÚN DEL BOVINO (Rhipicephalus (Boophilus) microplus) PROVENIENTE DE LA PROVINCIA DE SANTA FE-ARGENTINA Torrents, J The aim of this study was to obtain the sensitivity data of the native strains of R. microplus to ivermectin (IVM) in the province of Santa Fe-Argentina, in order to detect the emergence of resistant strains. Native (field isolation) and susceptible (reference) larvae of R. microplus were treated with increasing concentrations of IVM in order to determine its efficacy at different doses. The statistical treatment of the concentration-efficacy curves was performed by the PROBIT model, who is a standardized method proposed by FAO. The results obtained indicated that the larvae isolated were susceptible, being the values of LD50 (9.66 ppm) and LD90 (17.41 ppm), which were lower than those of the reference strain (LD50:13.58 ppm, LD90:19.31 ppm), and the RR (resistance ratio) were less than one (RR50: 0.711; RR90: 0.901). The DL99 (51.48 ppm) was only obtained in the reference strain to determine the discriminant dose (DL99x2), which is a parameter that could be used to easily discriminate susceptible and resistant larvae populations. Universidad Nacional del Litoral 2021-12-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion artículo Articulo info:ar-repo/semantics/artículo https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10944 10.14409/favecv.v19isuplemento.10944 FAVE Sección Ciencias Veterinarias; Vol. 19 Núm. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; Vol 19 No suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; v. 19 n. suplemento (2021): FAVE Sección Ciencias Veterinarias 2362-5589 1666-938X 10.14409/favecv.v19isuplemento info:eu-repo/grantAgreement/EC/FP7/ info:eu-repo/semantics/openAccess Derechos de autor 2021 J Torrents http://creativecommons.org/licenses/by-nc-sa/4.0
institution Universidad Nacional del Litoral
collection Publicaciones periódicas
format Artículo revista
description The aim of this study was to obtain the sensitivity data of the native strains of R. microplus to ivermectin (IVM) in the province of Santa Fe-Argentina, in order to detect the emergence of resistant strains. Native (field isolation) and susceptible (reference) larvae of R. microplus were treated with increasing concentrations of IVM in order to determine its efficacy at different doses. The statistical treatment of the concentration-efficacy curves was performed by the PROBIT model, who is a standardized method proposed by FAO. The results obtained indicated that the larvae isolated were susceptible, being the values of LD50 (9.66 ppm) and LD90 (17.41 ppm), which were lower than those of the reference strain (LD50:13.58 ppm, LD90:19.31 ppm), and the RR (resistance ratio) were less than one (RR50: 0.711; RR90: 0.901). The DL99 (51.48 ppm) was only obtained in the reference strain to determine the discriminant dose (DL99x2), which is a parameter that could be used to easily discriminate susceptible and resistant larvae populations.
author Torrents, J
spellingShingle Torrents, J
DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA
author_facet Torrents, J
author_sort Torrents, J
title DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA
title_short DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA
title_full DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA
title_fullStr DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA
title_full_unstemmed DETERMINATION OF THE EFFECTIVE CONCENTRATION 50, 90 AND 99 OF IVERMECTIN AGAINST A STRAIN OF COMMON BOVINE TICK (Rhipicephalus (boophilus) microplus) IN THE PROVINCE OF SANTA FE-ARGENTINA
title_sort determination of the effective concentration 50, 90 and 99 of ivermectin against a strain of common bovine tick (rhipicephalus (boophilus) microplus) in the province of santa fe-argentina
publisher Universidad Nacional del Litoral
publishDate 2021
url https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10944
_version_ 1718763526731857920
score 11.8626

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